Depression Linked to Immune Response in Some People

Changes in different components of the immune system, both adaptive and innate immune responses, may cause depression.

changes in immune cells are a cause or consequence of depression

Depression is characterised by widespread alterations in circulating myeloid and lymphoid cells, consistent with dysfunction in both innate and adaptive immunity.

Immune cells could be useful biomarkers for illness subtyping and patient stratification in future immunotherapy trials of depression, along with cytokines.

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